JLSa2 is a new and recently launched seed-stage venture backed company, located in South San Francisco, focused upon developing novel multifunctional protein-drug conjugate therapies to address human metabolic diseases and other non-oncology related diseases.
The company is seeking a RA/SRA to contribute to the production of these multifunctional conjugates as well as contribute to multiple aspects of product development as molecules progress from research stage to early clinical development.
Responsibilities
The candidate will primarily focus upon the generation, purification, analytical characterization of the resulting conjugates, and optimization of these processes. The candidate will work in a highly collaborative team with the analytical and functional assay teams, as well as senior leadership, to supply and characterize the conjugates and facilate data integration across functional areas and ensure rapid decision making and product iteration cycle time. This position is expected to be on site at our SSF facility.
Qualifications
BS/MS in analytical chemistry, biochemistry, or related scientific field and minimum 2-4 years of industry experience in the characterization of biologic molecules or peptides is required.
Experience with conjugation, purification and characterization of bioconjugates is preferred, as is experience using analytical techniques/instrumentation, including liquid chromatography assays such as RP-HPLC, SEC, CEX, HIC.
Experience in capillary electrophoresis, SDS-PAGE, UV-Vis, plate based assays, and high throughput sample management is a plus.
Demonstrated proficiency in hands-on protein purification or conjugation, experience in independently designing experiments, interpreting, and presenting data is preferred.
Knowledge of protein expression and purification is desirable.
Flexibility to work on multiple projects in a fast-paced start up environment is essential.
Good communication skills are essential.
Salary Range: $75,000 - $115,000 (Compensation and level will be commensurate with experience and expertise and could fall outside of the stated range).
Competitive benefits package is offered that includes health, dental, and vision insurance, life insurance, 401K plan, non-accruing PTO, and early-stage equity.