ICR's Early Cancer Detection program is focused on building early warning systems out of arrays of blood- and urine-based biomarkers from cancer patients and healthy controls. We're using machine learning to predict cancer signatures to enable early intervention when cancer is most treatable. We're hiring a Principal Scientist to lead our Cancer Early Detection Team.
With ICR, you'll get to:
- Lead a cutting-edge cancer biomarkers group to detect cancer at its earliest stages
- Contribute highly practical and readily translatable pan-cancer screening/early detection, diagnostic, prevention and therapeutic ideas
- Quantify and track cancer biomarkers, including CTCs, cfDNA, serum, plasma, and urine proteins, RNA, metabolites, driver-gene mutations, epigenetic modifications, etc
- Collaborate with ICR's Biomarkers Team to perform molecular and cellular cancer prevention screening assays, under a personalized medicine paradigm
Please apply if you have:
- A PhD, MD or both
- At least 10 years of cancer research experience, preferably in early detection and biomarkers
- Current and in-depth knowledge of pan-cancer: screening, early detection, biomarkers, diagnostic prediction, genetics, prevention, and chemical- and vaccine-therapeutics (practical and experimental)
- Programming experience in R and Python
- Solid grasp of biostatistics, especially probability theory
- Experience with prediction modeling and machine learning, including experience using proper scoring rules
Ideally, you'll also have:
- Expert knowledge and understanding of worldwide cancer biomarker and detection assay development pipelines
- Experience with cell-based assays, immunofluorescent microscopy, qPCR, flow cytometry, single-cell genomics, RNAseq, cell culture, organoid culture, Illumina NextSeq 550, DNA methylation sequencing, ddPCR, Luminex, clinical chemistry instrumentation, Kryptor, Access 2, robotic liquid handling (e.g. Tecan), Vortex, and DepArray
- Experience with protein, RNA, and small metabolite cancer biomarker analysis
And you'll need:
- An easygoing, friendly personality
- The ability to work in the United States without sponsorship
Position title and compensation are commensurate with experience.
The compensation ranges listed below are starting ranges.
Starting base pay range: $165,000/yr - $205,000/yr
Starting bonus range: $7,500/yr - $20,000/yr