Director Neuroscience and Ophthalmology

We are seeking a Physician Scientist to join our Neuroscience and Ophthalmology Therapeutic Area Genetics (TAG) team. We see this role as a subject matter authority in the translation of human genetic evidence into actionable insights in neurological, psychiatric, ophthalmological, and aging-related diseases. You will work closely with other teams in the Regeneron Genetics Center and Regeneron at large and be primarily responsible for designing, contributing to the execution of, and interpreting large and complex human genetic studies in the therapeutic areas. We hope you are excited by the opportunity to play a role in the development and implementation of innovative translational sciences and identify new therapeutic targets through genetic approaches.

As a Physician Scientist in Neurology/Ophthalmology, a typical day might include the following:

• Applying human genetics to target discovery, selecting indications for drug programs, and identifying subgroups of patients who are more likely to respond to treatment through genetic analyses.
• Working with a multidisciplinary genetics team consisting of human genetics scientists, bioinformaticians, statistical geneticists, and other team members to design, execute, and interpret genetics studies in ophthalmology.
• Working in close collaboration with other Therapeutic Area Genetics team members and forming a strong partnership with Genome Informatics, Analytical Genomics, Clinical Informatics, and other RGC teams to deliver on complex, top-quality scientific endeavors in these Therapeutic Areas.
• Generating, summarizing, and presenting results in internal and external meetings to a variety of audiences.
• Leading or contributing to the writing of scientific reports and publications.
• Representing the TAG team in cross-functional initiatives within RGC and Regeneron.
• Collaborating with external industry and academic partners in scientific consortia.

This job may be for you if:

• You have demonstrated the ability to design and lead human genetics studies delivering medically relevant findings in a team-based environment.
• You use medical knowledge to define relevant phenotypes for genetic association studies and to formulate innovative and important research questions. You have familiarity with clinical genetics concepts and various genetic models of disease.
• You have experience leading complex human genetics research endeavors, have knowledge of different study designs and analyses including GWAS, exome, or genome sequencing in cohort, case-control, or family-based studies, and have the ability to integrate different data resources to translate initial findings.
• You have an interest in understanding the genetic basis and causes of Neurological, Psychiatric, Ophthalmological, and Aging-related diseases and translating this knowledge into therapeutic insights. An outstanding candidate will have previous experience with phenotypes related to these diseases.
• You thrive working in a highly interactive environment with a diverse team of colleagues.
• You have outstanding communication skills and an ability to summarize and present the results of human genetic studies to a variety of audiences.

To be considered for this opportunity, you must have an MD or MD/Ph.D. with a strong background in and knowledge of human genetics or genetic epidemiology. An outstanding candidate will be an MD/Ph.D. with training and experience in translational human genetics, genetic epidemiology (or related disciplines), and strong quantitative skills. Familiarity with the applications of statistical genetics to gain medically actionable insights including polygenic risk scores, quantitative traits analyses, and Mendelian randomization, and familiarity with command-line interface, programming languages, and statistical software (eg. Python, R) is preferred. The outstanding candidate will have experience with the use of genetics in combination with other omics technologies (eg. epigenetics, proteomics, RNA-seq).

Does this sound like you? Apply now to take your first step towards living the Regeneron Way. We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.

For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.

Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.

Salary Range (annually)