Position Summary:
We are looking for an independent and highly motivated laboratory-focused PhD scientist to contribute to research efforts aimed at understanding target biology and the mechanism of action of novel small molecule inhibitors for cancer treatment. This scientist will play a key role in designing and executing cell-based assays to address critical scientific questions. The ideal candidate should be passionate about cancer biology and thrive in a fast-paced, multidisciplinary team environment focused on discovering and developing new therapeutics. The position level will be based on experience.
Key Responsibilities:
- Independently design and execute experiments.
- Perform in vitro assays to investigate the mechanism of action of potential anti-cancer therapeutics and identify novel biomarkers and biological pathways.
- Analyze and interpret experimental data, troubleshoot issues, and refine methodologies as needed.
- Collaborate closely with scientists across research teams to align efforts with project goals.
- Present findings and report on project progress in individual, team, and project meetings.
Qualifications & Experience:
- Ph.D. in cancer biology, molecular biology, cell biology, or a related field, with 2+ years of experience in cancer research; industry experience is a plus.
- Strong commitment to laboratory-based research.
- High attention to detail and enthusiasm for integrating fundamental biological insights with drug discovery.
- Knowledge of cancer epigenetics and gene regulation is preferred.
- Expertise in mammalian cell culture and cell-based assays, including viability assays (siRNA/shRNA, CRISPR, overexpression), protein analysis (Western blot, MSD, ELISA), and gene expression analysis (qRT-PCR).
- Experience in designing and performing flow cytometry assays.
- Ability to work independently while adapting to shifting priorities and timelines.
- Experience in bioinformatics data analysis and visualization is a plus.
- Ability to develop, optimize, and troubleshoot mechanism of action assays independently; experience working with CROs is a plus.