About GenScript
GenScript Biotech Corporation (Stock Code: 1548.HK) is a global biotechnology group. Founded in 2002, GenScript has an established global presence across North America, Europe, the Greater China, and Asia Pacific. GenScript's businesses encompass four major categories based on its leading gene synthesis technology, including operation as a Life Science CRO, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy.
GenScript is committed to striving towards its vision of being the most reliable biotech company in the world to make humans and nature healthier through biotechnology.
About ProBio
ProBio proactively provides end-to-end CDMO service from drug discovery to commercialization with proactive strategies, professional solutions and efficient processes in cell and gene therapy (CGT), vaccine, biologics discovery and antibody protein drug to accelerate drug development for customers. ProBio's total cell and gene therapy solution covers CMC of plasmid and virus for IND filing as well as clinical manufacturing and commercial manufacturing. In terms of plasmid service, ProBio supports the most clinical approvals for CGT drugs including mRNA vaccines, CAR-T in China. It is also the first GMP manufacturing platform to provide in vitro transcription (IVT) template linearized plasmids for mRNA vaccines and has supported several mRNA vaccine global enterprises to obtain clinical approvals. In terms of viral vector service, ProBio has a stable and high-yield viral vector platform.
The position reports to the Head of Product Development and Manufacturing, and is responsible for meeting site production, safety, and quality requirements by developing and establishing automated systems for mRNA synthesis, quality control experiments, high throughput gene synthesis platform and other emerging molecular biology service lines at the Redmond site of the GenScript Innovation Center.
Responsibilities:
- Independently manage or contribute to all laboratory automation projects including conception, design, development, acquisition, process implementation and execution of automation solutions for manufacturing
- Define scope of project in consultation with supervisor and stakeholders. Individually or collaboratively through leadership of project team, define alternative solutions, and decision criteria used to evaluate alternatives.
- Develop and optimize automation solutions for RNA synthesis by in vitro transcription and purification, and high throughput nucleic acid synthesis platforms. Script for automated platforms based on project needs.
- Provide support for the DNA and RNA production line by leveraging automation tools to achieve revenue goals. Troubleshoot issues, if occur, with automation systems, propose effective solutions and coordinate system updates and enhancements to optimize performance.
- Oversee preventative maintenance and calibration of automated system instruments, ensuring optimal performance and reliability. Collaborate with the equipment engineering team, internal stakeholders including QA team, production team and external vendors to provide technical input, review and approve testing documents and protocols of automation systems as needed.
- Acquire new technologies to develop, optimize and improve existing high throughput laboratory automation systems.
- Provide day-to-day maintenance and production support for the manufacturing equipment and staff.
Qualifications
- BS in Engineering Discipline or Biology/ Biochemistry/ Molecular Biology/ Biomedical Instrumentation/ related subjects with 2+ years of automation experience in manufacturing
- Proven track of workflow design and process optimization with automation
- Experience in transforming bench work process to automation solutions
- Knowledge of commercial automated liquid handlers, experience in handling/maintaining automated liquid handlers, e.g., Tecan, Beckman, PerkinElmer, etc.
- Basic understanding of hands-on molecular biology experiments is required
- Knowledge of automated production line is a plus
- Ability to effectively interact with individuals at all levels and good organizational and project management skills.
- Patient, attend to details and is able to follow SOPs
- Flexible to work in non-standard work hours in the case of emergency situations
Benefit:
- Medical Insurance/ Vision Insurance/ Dental Insurance
- 401(k) & Retirement Savings Plan (RSP)
- Short Term Disability Insurance
- New Child Leave
- Paid Time Off
- Paid Company Holidays per year
- Paid Sick Days (earned based on hours worked)
- Compassionate Leave
- Jury Duty Leave
- Float day
- Personal days
Perks:
- Free colleague meals during shift
- Onsite messages Charis
- Onsite gyms
Compensation:
Salary range: $85,000 - $130,000, depending on experience and qualifications.
GenScript USA Inc/ProBio Inc. is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is the Company's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.
GenScript USA Inc./ProBio Inc. maintains a drug-free workplace.