Company Description
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . on X , Facebook , Instagram , YouTube , LinkedIn and Tik Tok .
Job Description
Our In Vivo Pharmacology group in Lake County, IL has an opening for a motivated in vivo pharmacologist who is dedicated to the discovery and development of innovative treatments. The position involves working with both small molecule and biological therapeutics, with a focus on diseases of aging such as mitochondrial, metabolic, peripheral organ diseases, and fibrotic disorders. Primary responsibilities include independently executing, reporting, and troubleshooting in vivo pharmacology studies based on previous hands-on experience and foundational theoretical knowledge.
The scientist will work on preclinical in vivo models in mice and rats for age-related diseases (e.g., fibrosis, immune, kidney, metabolic, or cardiovascular) as well as mechanism of action and Pharmacokinetics/ Pharmacodynamic (PK/PD) studies.
The position requires interaction with in vivo / in vitro biology, translational/ biomarkers, PK and medicinal chemistry teams to advance therapeutic agents through the R&D pipeline.
Responsibilities:
- Acts as Study Leader/Coordinator for assigned studies and demonstrates proficiency in general in vivo procedures in mice and rats including dosing
- Maintains competency in all aspects of rodent handling and treatment dosing of small molecules and biologics in mice and rats
- Experience with ELISA / MSD/ /multiplex/ biochemical assay methods/ Western Blots/ qPCR and/or immunohistochemistry of paraffin/frozen sections is desired
- Develops and optimizes new methods/techniques to generate reliable and reproducible data in a timely manner. Experience in ex vivo processing of tissues (homogenization, RNA extraction) and analyses (ELISA, MSD, flow cytometry, WB, PCR, biochemical assays, multiplex platform) is desired
- Using an electronic notebook to maintain proprietary study records
- Working closely with his/her supervisor to schedule and prioritize workload to manage several tasks simultaneously
- Exhibiting excellent communication skills and the ability to present data clearly and thoroughly in both one-on-one interactions and group meetings
- This is an on-site laboratory position
Qualifications
Qualifications
Position will be hired based on level of education and experience
- Bachelors Degree, or equivalent education, with typically 3 or more years experience or Masters Degree or equivalent education (no additional experience).
- Proven expertise with design and execution of studies utilizing in vivo / ex vivo techniques in rodents is required
- Experience with drug formulation and administration to rodents via SC, PO, IP, and IV routes
- Experience utilizing in vivo / ex vivo techniques in rodents. This includes physiological measurements, tissue collection, and analysis by biochemical or histological methods. Experience with ELISA / MSD / Western Blots/ biochemical assays, flow cytometry and/or immunohistochemistry is desired
- Strong problem-solving skills
- Familiarity with data graphing, data analysis, presentations, and statistical software (e.g. Microsoft Office Suite, Prism) is necessary
- Good communication skills and willingness to work with a cross-functional team of researchers is essential
Key Leadership Competencies
- Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance
- Learns fast, grasps the 'essence' and can change the course quickly where indicated
- Raises the bar and is never satisfied with the status quo
- Embraces the ideas of others, nurtures innovation and manages innovation to reality
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes ingood faith it will pay for this role at the time of this posting based on the job grade for this position. Individualcompensation paid within this range will depend on many factors including geographic location, and we may ultimatelypay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/visioninsurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, and determinable.The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefitsthat are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
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