Assistant Project Scientist

Assistant Project Scientist
University of California Los Angeles

Requisition Number: JPF08325

Assistant Project Scientist
Muscle Biology and Muscle Stem Cell Laboratory

Position Description
We seek an experienced scientist to advance our research at the University of California, Los Angeles Department of Neurology in the laboratory of Dr. Thomas Rando.

Research at Dr. Rando's laboratory intersects the biology of aging and stem cell biology. Our research focuses on molecular mechanisms that regulate stem cell function and tissue regeneration in adult animals. Using skeletal muscle stem cells as a model system, we study unique features of adult tissue stem cells such as quiescence and their response to tissue injury, and how these features are impacted during aging. We use a multi omics approach to identify epigenetic and metabolic changes that take place in stem cells and their niche environment in aging animals, and use in vivo studies to test the effectiveness of aging interventions in reversing these changes. The successful candidate will be expected to work on multiple projects efficiently and effectively under the supervision of the PI and senior faculty. He/She should be able to carry out experiments, to analyze data with minimal direct supervision and to communicate well with scientists at all levels.

Specific Responsibilities
The successful candidate will design studies and execute experiments in an independent manner. This includes but is not limited to the generation of transgenic mouse models, isolation of muscle stem cells for in vitro characterization by cell biology and molecular biology assays such as immunofluorescence, RT-PCR, Western Blotting and FACS, stem cell transplantation and in vivo tissue regeneration assays. The scientist will participate and assist in generating data for manuscript and grant preparation and revision, and train junior postdocs, technical staff, graduate and undergraduate researchers common techniques and assays used in the laboratory. The scientist will also work with lab manager to maintain and organize rodent colonies. Excellent book keeping skills are a must.

Qualifications
Applicants must have a PhD. Ideal candidates will have a strong background in cell biology and at least one of the following areas: molecular biology, biochemistry, epigenetics, rodent models, and/or immunology. 1-2 years of independent postdoctoral research experience in an academic or equivalent setting is preferred.
Applicants must have experience in flow cytometry, immunohistochemistry, histology, cell culture, molecular biology assays, rodent surgery, and statistics. Prior experience with skeletal muscle and CRISPR technology is preferred.

Additional Duties

•   Assist in collaborative projects with other laboratories
•   Participate in routine lab maintenance
•   Supervise undergraduate students

Document requirements
Curriculum Vitae (updated)
Bibliography
Statement of Research
Statement on Contributions to Equity, Diversity, and Inclusion
Cover Letter (Optional)
Three references (Optional)

SALARY RANGE:
Step 1 $68,400
Step 2 $72,000
Step 3 $75,800
Step 4 $79,300

Application procedure: Apply by submitting your application to our online RECRUIT system at along with CV, statement of research, and 3 references (optional). Screening of applicants will begin immediately and will continue until the position is filled.
Please be advised that the final candidate recommended for hire into a critical (or otherwise designated) position will be required to successfully complete a background investigation. Any convictions will be evaluated to determine if they directly relate to the responsibilities and requirements of the position. Having a conviction history will not automatically disqualify an applicant from being considered for employment.

The offer of this position is contingent on the successful completion of a background check prior to your first day of employment and evidence of authorization to work in the United States. Also by accepting this offer you are acknowledging compliance with UCLA Health policy by receiving your influenza vaccination prior to your start date. If you are in agreement with the terms and conditions of this offer, please sign and return the enclosed copy of this letter. Feel free to contact Davis D. del Pino at to discuss any questions you may have regarding employment.

As a condition of employment, you will be required to comply with the University of California Policy on Vaccination Programs - With Updated Interim Amendments. All Covered Individuals under the policy must provide proof of receiving the COVID-19 Vaccine Primary Series or, if applicable, submit a request for Exception (based on Medical Exemption, Disability, Religious Objection, and/or Deferral based on pregnancy or recent COVID-19 diagnosis and/or treatment) no later than the applicable deadline. All Covered Individuals must also provide proof of receiving the most recent CDC-recommended COVID-19 booster or properly decline such booster no later than the applicable deadline. New University of California employees should refer to Exhibit 2, Section II.C. of the SARS-CoV-2 (COVID-19) Vaccination Program Attachment for applicable deadlines. All Covered Individuals must also provide proof of being Up-To-Date on seasonal influenza vaccination or properly decline such vaccination no later than the applicable deadline. Please refer to the Seasonal Influenza Vaccination Program Attachment. (Capitalized terms in this paragraph are defined in the policy.) Federal, state, or local public health directives may impose additional requirements.

The University of California is an Equal Opportunity/Affirmative Action Employer advancing inclusive excellence. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy. UC Nondiscrimination & Affirmative Action Policy.

UCLA is a Tobacco-Free environment. For more information, please view the policy at Tobacco-Free Campus Policy.

To apply, please visit:

The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy,
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