Technical Development Scientist

Job title: Technical Development Scientist

Technical Development Scientist
Job Knowledge & Scope
RMG, in the Cell Culture and Bioprocess Operations department, is responsible for providing
support to pre-Early Stage Research to Early Development projects with high-throughput protein
production from mammalian transient cultures. We are looking for a motivated candidate with cell
culture and sterile technique experience to join our team to enable protein production at
and help advance our portfolio.
Key Responsibilities
Perform transient transfections in CHO and HEK293 cells in scales 1mL to 25L to support
pipeline productions adhering to established protocols
Maintain seed train cell cultures in bioreactors and shake flasks
Operate liquid handlers - Tecan and Hamilton for automated processes
Operate wave bag reactors for productions and cell maintenance
Maintain and troubleshoot key cell culture instruments such as Vi-Cell, Nova Flex2, Nova Flex,
Cedex and bioreactors
Participate in troubleshooting production or platform processes
Participate in lab management and data management.
Contribute to improving existing cell culture platforms and developing new platforms to
deliver diverse protein and cellular reagents to enable a large number of research programs.
The candidate must be highly self-motivated, organized, detail oriented and responsive to feedback.
The candidate is expected to precisely follow written procedures, practice sterile technique,
demonstrate accurate documentation skills, and report deviations in a timely manner. They should
be able to work independently within guidelines and policies, with minimal guidance.
Qualifications
Required:
PhD (with 0-2yrs relevant experience) in Biotechnology, Chemistry, Biochemistry or related
fields
Suspension adapted mammalian cell culture (CHO and/or HEK293)
Excellent written and verbal communication skills, and have strong collaborative skills.
Preferred
State-of-the-art transient and stable protein expression experience
Relevant bioreactor experience
Hands-on experience with automation and liquid handlers like Tecan Freedom Evo and
Hamilton Microlab Star
Knowledge of cell biology, cell engineering, molecular biology, recombinant protein
purification and protein characterization is preferred