Department 48 - Bioprocess Development
Employment Type Full Time
Location Redwood City, CA
Workplace type Onsite
Description
Codexis, a biotechnology company based in Redwood City, CA, is looking to hire a
Senior Fermentation Scientist. Codexis is a leading enzyme engineering company leveraging its proprietary CodeEvolver technology platform to discover, develop and enhance novel, high-performance enzymes and other classes of proteins. Codexis enzymes solve for real-world challenges associated with small molecule pharmaceuticals manufacturing and nucleic acid synthesis. The Company is currently developing its proprietary ECO Synthesis platform to enable the scaled manufacture of RNAi therapeutics through an enzymatic route. Codexis enzymes can drive improvements, such as higher yields, reduced energy usage and waste generation, improve efficiency in manufacturing and greater sensitivity in genomic and diagnostic applications.
To meet the goals we've set for ourselves, we look for individuals who are driven, eager to grow and ready to embrace meaningful challenges. We empower employees to be authentic, ambitious, agile and have the courage to take action where they can make a positive impact.
Come join us on this journey to transform the enzyme engineering landscape for the betterment of human health.
About the Opportunity: The
Senior Fermentation Scientist will join our Upstream Bioprocess Development team and will be responsible for the design & execution of fermentation experiments for development of new bioprocesses. The person will play a leading technical role in project management of fermentation programs within the group. In addition, the Sr. Scientist will be responsible for tech transferring bioprocesses to CRO/CMOs. They will collaborate cross functionally with members of the Technical Operations team. The position will be on-site in Redwood City.
If any of the below describes you, we would love to meet you. - Passionate about Fermentation and the role it plays in translating scientific discovery into commercial reality.
- Enjoys cross-functional collaboration, teamwork, and mentorship. In addition, has a passion for technical project management.
- Enjoys fermentation process development and microbial physiology (E. coli focus)
- Strong safety mindset in a fermentation environment and have a strong attention to detail.
In this role you will be responsible for:
- Lead the development of new fermentation bioprocesses utilizing E. coli as an expression host for production of enzymes for Pharmaceutical Manufacturing & Life Science applications.
- Hands-on running bench-scale bioreactors (250 mL, 2 L, & 10 L), performing bench experiments, and providing mentorship/management to other team members within the bioprocess group.
- Lead the authorship of tech transfer packages and transferring processes to CRO/CMOs.
- Perform Design of Experiments (DOEs) and data analysis with strong scientific and statistical rigor.
- Supervising Research Associates & Engineers in the bioprocess development group.
- Following safety best practices and leading implementation of new safety processes.
- Routinely present technical information to various audiences both internal and external to Bioprocess Development & Codexis.
The essential requirements of the job include:
- Ph.D. in Chemical Engineering, Microbiology, Microbial Physiology, or related discipline with a minimum of 5 years of relevant industry experience; M.S or B.S. with at least 8-10 years relevant experience, respectively.
- Strong understanding of microbial physiology (with a focus on E. coli) and its intersection with fermentation processes at bench scale ( 10L).
- Previous hands-on experience with bench scale fermentation for production of recombinant proteins in E. coli.
- Experience with leading multiple fermentation-focused projects simultaneously and technical program management.
- Experience utilizing graphical software (JMP, R, Python, or similar) and motivated in handling large data sets from high throughput fermentation platforms to make data-driven decisions.
Additional experience that would be valuable for this role includes: - Previous experience working with and providing oversight to CRO/CMOs.
- Experience working under a quality system (e.g. ISO, GMP) or manufacturing experience/exposure.
- Hands-on experience with primary recovery of enzymes and knowledge of downstream purification unit operations.
- Knowledge of automation systems and using liquid handling equipment and assays to support fermentation process analytics.
- Experience managing/mentoring Engineers, and Research Associates performing fermentation process development workflows.
CODEXIS PAY TRANSPARENCY: The anticipated salary range for candidates who will work in Redwood City is $138,500 to $170,000. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etc. Codexis is a multi-state employer, and this salary range may not reflect positions that work in other states .
What can Codexis offer you?
- Medical, Dental and Vision Insurance
- Basic Life, AD&D, Short- and Long-Term Disability Insurance
- 401k with Company Match up to 4%
- Company Equity
- Generous Paid Time Off including 18 Company Holidays (with a summer and winter shutdown), Vacation, and Wellness Time
- Annual Lifestyle Account for reimbursement of fitness programs, equipment and more
- Employee Stock Purchase Program (ESPP)
- Flexible Spending Accounts (Commuter/Parking, Dependent Care & Healthcare)
- Student Debt Program (Company Contribution to Loans)
- Mental Health Wellness Program
- Subsidized onsite lunch program
- Onsite Gym Facilities
- Paid Parental Leave
- And More.
About Codexis Inc
Why join Codexis?
At Codexis we offer a very competitive compensation package and beyond excellent benefits. We foster career growth, continued education and upskilling through our mentorship program and learning and development opportunities. You will learn and work alongside inspirational leaders and colleagues who are equally passionate about our mission and committed to fostering an inclusive, growth-centered, and rewarding culture. Diversity is valued and mutual trust is of paramount importance to the ethos at Codexis. The people, the culture and working with others with a common goal is what makes Codexis a great place to work.
For more information, visit .
NO AGENCIES OR THIRD PARTIES
Codexis is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status.