Research Scientist

ONSITE 5 DAYS, NEW HAVEN ONLY, PARKING WILL BE REIMBURSED.

This is what you will do:

The position is required to join Injectable Drug Product Development group of pharmaceuticals' Analytical and Pharmaceutical Development department. This position is required to conduct studies to enable Drug Product characterization activities, including combination products at high protein concentration, as well as commercial products. The job entails experimental work on various aspects of Drug Product characterization, including formulation development, safety risk assessment of excipients as well as process reagents, extractables and leachables, in use compatibility studies for intravenous and subcutaneous administration, process development to support drug product manufacturing support, particulates testing. The ability to work with minimal supervision as well as part of the team is essential. The position entails execution of the studies and data processing and compiling to generate and support development reports as well as other required documentation. Understanding of assay development, biotherapeutics development is a plus. Understanding of the basic principles of protein chemistry and/or drug product process is required. Experience with electronic record keeping software, like ELN, EndNote, e-logbooks; maintenance of laboratory instrumentation (organizing PMs, data backup, SW upgrade, etc.) and familiarity with design and maintenance of databases will be a plus.

You will be responsible for:

Execute development studies for Alexion pharmaceuticals' drug candidates and commercial products, support tech transfer activities for internal manufacturing and contract manufacturing sites

Assist in preparation of internal technical reports on the executed studies with minimal supervision for the Alexion product candidates

Participate in Department meetings and other technical and team building activities

You will need to have:

BS in Chemistry, Biochemistry, Biophysics, Chemical engineering, or relevant field with 2+ years of experience or MS degree with 1+ years of relevant experience is required. Solid background in protein chemistry, chemistry, biochemistry, or equivalent is highly preferred.

Position requires scientific and practical knowledge of protein chemistry or drug product process

Previous experience in biotherapeutics development as well as understanding of the biotechnology products life cycle and factors impacting protein molecule stability is a plus

Hands-on experience with instrumentation, used in protein pharmaceutical and analytical development as well as characterization and knowledge of cGMP and quality guidelines is a plus

Ability to take initiative in problem solving and finding solutions to scientific challenges with minimal supervision is preferred

Shows ability to take instructions and execute experiments and other activities with minimal supervision is required

The individual must be able to work in a collaborative setting and has ability to adhere to timelines with minimal supervision is essential

Excellent interpersonal skills are required, as is the strong ability to communicate effectively

Nesco Resource provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.