Research Associate

Reporting to a lead within the Process Development team, CARGO is hiring a Process Development Research Associate within the Process Sciences Organization in Technical Operations. The candidate will contribute to and support development of GMP compatible manufacturing processes for production of CARGO's cell therapy products. The ideal candidate will have a background in cell selection, lentiviral transduction, cell culture expansion, and flow cytometry analysis. The successful candidate will work closely with the Process Sciences team and the broader CMC team. The individual will also collaborate cross-functionally to ensure timely development, manufacture, and release of drug products as well as support regulatory submissions. The role is based in San Carlos, CA. WHAT YOU'LL DO AT CARGO THERAPEUTICS Support planning and execution of experiments and associated analysis and reporting Provide process development support in team-based environment for technical development studies performed both internally and externally Participate in development and characterization of cell therapy manufacturing processes Support technology transfer to partners at external contract manufacturing organization including compilation of documentation (reports, SOPs, batch records, assessments) Participate in laboratory set-up and equipment procurement, and establish internal process development practices Author relevant documentation (protocols, technical reports, SOPs) Organize, communicate, and present data to key stakeholders, senior management, and external partners Interface and work collaboratively with CDMO and testing lab partners Proactively enable cross-functional collaborations with internal stakeholders, external partners, and consultants THE RIGHT STUFF: Required Experience & Qualifications Bachelor's or Master's degree in a relevant scientific area such as biotechnology, bioprocess, molecular biology, immunology, biochemistry 2+ years of relevant experience in T-cell biology and/or immunotherapy Prior experience in cell therapy industry; process development preferred Expertise in mammalian cell culture techniques preferred Experience in cell therapy unit-operations such as cell selection, lentiviral transduction, cell culture and expansion preferred Expertise with in-process measurements for cell count, metabolite analysis, and flow cytometry analysis preferred Ability to work in a highly adaptive environment and learn new skills for changing priorities Flexible and creative, with ability to think outside the box Must have interpersonal, organizational, written, and verbal communication skills, and the ability to work collaboratively in a team environment Proficiency in Office, Design of Experiments, JMP, Benchling, and other productivity and data analysis tools is a plus Flexibility with work schedule/on-site availability (i.e., occasional weekend work) PAY RANGE The combined pay range for this role is $72,000 - $99,000. Title and salary will be based on our assessment of skills and experience relevant to our needs for the role. ABOUT CARGO THERAPEUTICS CARGO Therapeutics, Inc. is a clinical-stage biotechnology company positioned to advance next generation, potentially curative cell therapies for cancer patients. CARGO's programs, platform technologies, and manufacturing strategy are designed to directly address the limitations of approved cell therapies, including limited durability of effect, safety concerns and unreliable supply. CARGO is currently evaluating its lead program, CRG-022, an autologous CD22 chimeric antigen receptor (CAR) T-cell therapy candidate, in a potentially pivotal Phase 2 clinical trial in patients with large B-cell lymphoma (LBCL) whose disease relapsed or was refractory (R/R) to CD19 CAR T-cell therapy. CARGO also plans to evaluate CRG-022 in patients at earlier stages of disease, including LBCL and other hematologic malignancies. Beyond its lead program, CARGO is leveraging its proprietary cell engineering platform technologies to develop a pipeline of programs that incorporate multiple transgene therapeutic "cargo" designed to enhance CAR T-cell persistence and trafficking to tumor lesions, as well as to help safeguard against tumor resistance and T-cell exhaustion. CARGO's founders are pioneers and world-class experts in CAR T-cell therapy, and its team has significant experience and success developing, manufacturing, launching and commercializing oncology and cell therapy products. For more information, please visit the CARGO Therapeutics website at Join us to help make a difference. EEO & EMPLOYMENT ELIGIBILITY CARGO Therapeutics, Inc. is committed to building a diverse, equitable, and inclusive company. We provide equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability, or veteran status. CARGO Therapeutics, Inc. also complies with all applicable national, state, and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification required of applicable law. CARGO Therapeutics requires all new hires to be fully vaccinated against COVID-19 as of their start date. This requirement is a condition of employment at CARGO Therapeutics, and it applies regardless of whether the position is located at a CARGO Therapeutics site or is fully remote. If you are unable to receive the vaccine due to a disability or serious medical condition, or because it is prohibited because of your sincerely held religious beliefs, you will have an opportunity to request a reasonable accommodation.