Postdoctoral Fellow Ultra

Job Description Be a part of the legacy: Postdoctoral Research Fellow Program Our Research Laboratories' Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery. Project Title: Understanding and exploiting the capabilities of ultra-high throughput mass spectrometry (uHT-MS) Position Overview: We are seeking a talented and motivated Postdoctoral Scientist passionate about the application of the latest analytical technologies within pharmaceutical drug discovery. Working within the DATA (Data Science, Automation, & Translational Analytics) organization in the Pharmacokinetics, Dynamics, Metabolism & Bioanalytics (PDMB) Department, you will be building a foundational understanding of Acoustic Ejection-Mass Spectrometry (AE-MS). AE-MS brings data acquisition times down by 10-100x or more compared with traditional discovery high throughput quantitative LC-MS/MS approaches opening up possibilities for redefining not just bioanalytical strategy but also how experiments are designed and executed. Based at our West Point, Pennsylvania facility, you will have access to a brand new state-of-the-art automated laboratory containing the latest AE-MS technologies coupled to automated platforms for development and execution of assay workflows. Taking the foundational knowledge you build; you will be working with cross-functional teams and as part of a research collaboration with the instrument vendor to define strategies for rapid AE-MS method development and applying this to the development of new workflows within Drug Metabolism and Pharmacokinetics (DMPK). Responsibilities include but are not limited to: Develop a strategy for rapid AE-MS method optimization and apply it to real-world bioanalytical applications in DMPK for an array of assay types. Design and execution of experiments to build Structure Activity Relationship for mass spectrometry ionization efficiency. You will work with chemistry, automation and compound logistics, bioanalytic and data science teams. Develop an understanding for application of AE-MS in real-time analysis of enzyme kinetic experiments. Continue to build upon our company's research collaboration with the instrument vendor. Actively engage in the education and training of our company's colleagues. Write, publish and present (internally and externally) findings. Education Minimum Requirement: Candidates must currently hold a PhD or will you have completed your PhD within six months in Chemical, analytical/ bioanalytical or biological sciences. Required Experience and Skills: Mass Spectrometry Analytical/bioanalytical science Basic statistical analysis and data handling skills Must have strong organizational skills to deal with large amounts of data. High attention to detail; scientific and technical problem solving. The candidate must exhibit excellent communication and collaborative skills for working in cross-functional multi-disciplinary teams. Preferred Experience and Skills: Design of Experiments (DoE) experience Previous experience with high throughput technologies and laboratory automation Data science and programming (R, Python, etc.) Resume keywords for recruiting team: Mass spectrometry Automation Data processing Data science MRLpostdoc VETJOBS NOTICE FOR INTERNAL APPLICANTS In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions. If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor. Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission. Current Employees apply HERE Current Contingent Workers apply HERE US and Puerto Rico Residents Only: Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process. We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement Pay Transparency Nondiscrimination We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. 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Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote". Search Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. Employee Status: Regular Relocation: VISA Sponsorship: Travel Requirements: Flexible Work Arrangements: Not Applicable Shift: Valid Driving License: Hazardous Material(s):