Postdoctoral Fellow

Janssen Research & Development, L.L.C, a Johnson & Johnson's company is recruiting for a Postdoctoral Fellow, Clinical Pharmacology and Pharmacometrics, at its Spring House PA or Titusville NJ location. The Postdoctoral Fellow will be involved in various activities to support Research and Development in areas ranging from preclinical to early/late-stage clinical development, including: The Clinical Pharmacology and Pharmacometrics (CPP) department at Janssen R&D (JRD) develops and applies quantitative methodologies (population pharmacokinetics, mixed effects modeling, PK/PD analysis, and disease progression modeling) across all phases of drug development. The Post-Doctoral Fellow will work on one or multiple projects to apply and expand in-house clinical pharmacology knowledge, exposure-response, PK/PD, and/or QSP modeling platforms to inform decision making in drug development such as dose selection and applying model informed drug development (MIDD) principles. Key Responsibilities: Advance the development of fit-for-purpose mathematical models (eg, population PK and PK/PD, empirical or mechanism-based PK/PD, quantitative systems pharmacology) to inform clinical study design (including but not limited to human PKPD analysis, first-in-human (FIH) starting dose projection, and efficacious dose selection) through identifying and addressing critical knowledge gaps using modeling and simulation approaches Develop flexible tools for data visualization, pharmacometrics analysis and report automation and standardization Identify and improve processes and workflow, develop innovative thinking, inform strategic decision making, and implement new methodologies when applicable