Director Immunobiology

Reporting to the Executive Director, Research, the Director, Immunobiology will drive research activities to design, characterize, and develop therapeutic antibodies as well as support preclinical mechanistic studies of biologic drug candidates for the treatment of autoimmune and inflammatory diseases. Duties will include design and testing of therapeutic antibodies as well as planning and implementation of mechanism of action studies in cell culture and experimental animals. The Director, Immunobiology will also contribute to the efforts to elaborate mechanistic pathway biology, biomarker discovery, and disease indications. An important component of this position will be to leverage expertise in cutting edge immunology to initiate and maintain key collaborations with leading academic investigators and CROs. This will include identification of leading principal investigators working in areas of immunobiology relevant to disease pathogenesis and pathway biology. This role is based in our Lexington, MA office. Our office-based employees follow a hybrid schedule of 4 days in the office, and 1 day remote. Responsibilities (including, but not limited to): Apply knowledge of therapeutic biologics to develop and characterized novel drug candidates. Apply immunology, molecular and cell biology, genetics, and pharmacology know-how to develop and communicate a thorough mechanistic understanding of disease pathogenesis and target rationale Manage collaborative relationships with key internal and external stakeholders and with the company research leadership to resource and advance projects to clinical development Contribute to future immunobiology research strategy by working with the Research team to credential new targets and diversify the company's preclinical portfolio Coordinate, plan, and execute laboratory activities Coordinate cross-functional efforts to meet short- and long-term project goals Conduct high quality, innovative research in biology Interpret and report results and present independently within/outside research & early development disease and translational areas/functions Oversee specific functional activities (specialist area) and provides clear ideas and directions (e.g. proof of concept experiment to fit to the clinical indication) for additional specialist/functional areas Coordinate one or more programs and project teams in parallel Provide leadership and mentoring for scientists and research associates Qualifications: Requires a PhD in immunology, molecular biology, or cell biology plus postdoctoral experience (or equivalent relevant experience) with 10+ years' industry experience in research or drug development Demonstrates and applies independent thought and creativity in projects and programs Solid publication or patent record in high impact peer-reviewed journals Expertise in primary human tissue and cell-based assays Experience working with multi-disciplinary and matrixed teams Outstanding project management, communication, and interpersonal skills Strong interpersonal, influencing and collaboration skills to work in a team-oriented, matrix environment, and the ability to work through conflicts Must be able to work under pressure, meet tight deadlines, multi-task and be able to pivot in response to changing priorities while maintaining a positive and collaborative attitude Kiniksa is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, transgender status, age, genetics, national origin, protected veteran status, or disability status, or any other legally protected category. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.