Associate Director

Emeryville, California

4D Molecular Therapeutics
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Attention recruitment agencies: All agency inquiries are vetted through 4DMT's internal Talent Acquisition team. No unsolicited resumes will be accepted. Agencies must be expressly engaged by the 4DMT Talent Acquisition team on any requisition. Agencies reaching out directly to hiring managers will not be tolerated and doing so may impact your ability to work with 4DMT in the future.


4DMT is a clinical-stage biotherapeutics company harnessing the power of directed evolution for targeted genetic medicines. We seek to unlock the full potential of gene therapy using our platform, Therapeutic Vector Evolution (TVE), which combines the power of directed evolution with our approximately one billion synthetic AAV capsid-derived sequences to invent evolved vectors for use in our products. We believe key features of our targeted and evolved vectors will help us create targeted product candidates with improved therapeutic profiles. These profiles will allow us to treat a broad range of large market diseases, unlike most current genetic medicines that generally focus on rare or small market diseases.

We have built a deep portfolio of AVV-based gene therapy product candidates, with five product candidates in clinical trials: 4D-150 for the treatment of wet age-related macular degeneration (wet AMD) and diabetic macular edema (DME), 4D-710 for the treatment of cystic fibrosis lung disease, 4D-310 for the treatment of Fabry disease cardiomyopathy, 4D-125 for the treatment of X-linked retinitis pigmentosa (XLRP), and 4D-110 for the treatment of choroideremia. In addition, we have two product candidates in preclinical studies: 4D-175 for geographic atrophy (GA) and 4D-725 for alpha-1 antitrypsin deficiency.

To-date, we have demonstrated clinical proof-of-concept for three evolved vectors in three therapeutic areas and routes of administration with five products and patient populations. We believe this validates the power of our directed evolution platform for discovering superior vectors compared to wildtype viral vectors. We have built a robust and efficient product engine with 6 open Investigational New Drug Applications (INDs) in the U.S., 1 IND in Taiwan, and 1 Clinical Trial Approval (CTA) in Australia. We believe we are positioned to create, develop, manufacture and, if approved, effectively commercialize targeted genetic medicines that could transform the lives of patients suffering from debilitating diseases.

In addition to TVE, our technology includes a robust AAV manufacturing platform and onsite manufacturing facility that allows us to rapidly produce and test research grade material and scale up to GMP clinical material. This internal capability and close collaboration between our R&D and Manufacturing teams has greatly accelerated the pace of discovery at 4DMT.

Company Differentiators:


• Fully integrated clinical-phase company with internal manufacturing

• Demonstrated ability to move rapidly from idea to IND

• Five candidate products in the clinic and two declared pre-clinical programs

• Robust technology and IP foundation, including our TVE and manufacturing platforms

• Initial product safety and efficacy data substantiates the value of our platforms

• Opportunities to expand to other indications and modalities within genetic medicine


GENERAL SUMMARY:

The Associate Director (AD) will be will be a key member in a growing and dynamic organization with responsibilities covering budgeting/forecasting, reporting, process improvement and Workday Adalptive Planning management. This is a high impact role that will contribute to scaling the FP&A function as the company growns. The candidate should have exceptional business collaboration skills with an eye towards systems-based process improvements and providing insightful analysis to drive decision-making.

This role is hybrid, with remote work and 2+ days a week in our Emeryville office.

Key Responsibilities:

  • Lead the financial planning and analysis for the G&A functions of the company, including budgeting, forecasting, and variance analysis
  • Collaborate with G&A department heads
  • Bring experience and best practices to the company as it implements Adaptive Planning
  • Administer Adaptive Planning ensuring data accuracy, creating dashboards, establishing workflows and providing support to users
  • Create standardized reports for the Board and the Executive Team
  • Build and maintain financial and personnel models in Adaptive Planning
  • Participate in other ad-hoc projects and analyses as needed

Qualifications:

  • 10+ years of experience in financial planning and analysis, with a focus on G&A functions
  • 5+ years of experience with Adaptive Planning or a similar financial planning system
  • Experience integrating NetSuite and other systems to a planning system
  • Strong analytical and problem-solving skills
  • Excellent communication and collaboration skills
  • Ability to work independently and manage multiple priorities
  • Bachelor's or equivalent degree in accounting, finance or business administration
  • MBA or CPA a plus

Base salary compensation range:

Bay Area Range: $181,000/yr - $210,000/yr

Please note that the base salary compensation range and actual salary offered to the final candidate depends on various factors: the candidate's geographical location, relevant work experience, skills, and years of experience.

4DMT provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, national origin, age, disability, genetic information, marital status, status as a covered veteran, and any other category protected under applicable federal, state, provincial and local laws. Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities
Date Posted: 18 May 2024
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